Can You Mix Advil And Alcohol?


“Can you mix Advil and alcohol?” –  is a question that’s sometimes asked. We hear plenty of bad news from time to time about experiences people have had when mixing alcohol with a certain drug or medication. Some of the experiences we hear about have proven to be fatal, though the majority of deaths have been attributed to an overdose of one or the other, or of both, and not necessarily due to the fact that alcohol and a given drug happened to be taken at the same time. There are also numerous drugs or medications that, when taken with alcohol, have minimally harmful side effects, or exhibit no side effects at all. In any event, the best approach to determining what’s safe and what isn’t, is always to ask the question.  Don’t just ask a friend who may have tried to mix alcohol with a drug, and is still around to tell about it. Seek out an authoritative source, always bearing in mind that different people will at times react differently, not only to a given medication, but to alcohol as well.

Advil And Ibuprofen


Advil is a pain reliever, a pain reliever whose primary constituent is ibuprofen. Most people can take ibuprofen safely, although there are a few who should not. Taking too high a dosage of ibuprofen, or taking ibuprofen on a more or less steady basis for a long period of time, can however have adverse effects on the body. The stomach and the intestines are particularly prone to incurring damage as a result of ingesting too much ibuprofen over too long a time. Those who have heart, liver, or kidney disease should generally refrain from taking ibuprofen.


For that matter, those who suffer from any of the above problems should probably not use alcohol either, at least not in excessive amounts, since an excessive use of alcohol can also create heart, liver, and kidney problems, and the excessive use of alcohol can definitely cause damage to the stomach and the intestines. The maker of Advil recommends that those who have any of the aforementioned problems should not mix Advil and alcohol. Doing so may only make a bad situation worse.

The Possible Danger To The Liver


We all know that a prolonged and excessive use of alcohol can cause liver damage, specifically cirrhosis of the liver, a condition where tissues in the liver are irreparably damaged or destroyed, with the only remedy usually consisting of a liver transplant. Advil can have the same effect on the liver, but only when taken excessively, or for an extended period of time. Whether alcohol or Advil are to blame, any damage done to the liver usually takes place over a fairly long period of time. The danger is, when Advil and alcohol are mixed, damage to the liver cells can occur at a significantly higher rate, and noticeable damage could occur within months, rather than taking several years.


The danger obviously is significantly less if one takes an Advil in the morning, and has a cocktail in the evening, instead of washing down a pill with an alcoholic beverage. In other words, if a person needs to take a pain reliever, it’s best to take it a few hours before or a few hours after taking a drink. An exception would be if a person has liver disease. In this case, ingesting either alcohol or Advil would tend to make the problem worse, and taking both at the same time could make problem not only much worse, but make it much worse very quickly.

Things That Interact With Advil


There are a number of things whose interaction with Advil could produce unfavorable results. There are nearly 400 drugs which interact negatively with Advil, about a quarter of which interact in a way that would be described as major. Other drugs either interact moderately, or the interaction is of a minor nature. From this perspective, the interaction between Advil and alcohol would be minor, unless either or both are taken in excess, or the person taking the two substances has serious stomach, liver, or heart problems. Then any interaction should probably be classified as being moderate to major.


Mixing Advil, Aleve, Or Tylenol With Alcohol


The interaction between alcohol and two other top pain relievers should also be noted, since many people do not know what the difference is, or if there is any significant difference, among the three. Advil, as noted above, consists of ibuprofen, a non-steroidal drug. The primary ingredient of Aleve is naproxen, which is also a non-steroidal drug. Acetaminophen is the primary ingredient of Tylenol, and is an analgesic, whose non-steroidal properties are not pronounced, meaning that Tylenol has less anti-inflammatory properties than do the other two. None of the three should be taken excessively, and the effects of taking any of them with alcohol is somewhat similar, except that the side effects of Tylenol, when combined with alcohol, can be significantly more severe. As far as Aleve is concerned, the danger is more a case of stomach bleeding, which still can be become quite serious, rather than damage to the liver. All three should be used with caution by anyone who uses alcohol on a more or less steady basis.